how about ancient Sith holocrons? I'd much rather find a cache of holocrons with people like Marka Ragnos speaking than the deck officer of the Peragus Mining Facility.
don't get me wrong, Peragus was well done. but I think the point is clear: there are ways to make the familiar new. Dantooine is another example....I'd love to see it again but there has to be something new....I don't know, maybe a long-distance adventure of some kind.
and I personally think Iziz would make a great urban hub for the game.
as someone else alluded to, part of the solution might be to have different segments of the game. just as you had no choice about when to go to Peragus or Malachor V, maybe there could be certain segments inside the "middle game" in which you are seperated from your ship and go to a certain world during that time.
you can't go back, since the world is not on your astrocharts. since this segment would be linear, it would allow the devs to have a lot of quests, FMV sequences and lush terrain (since they know no one will miss out on it).
I like having freedom in the middle game but I wouldn't mind if the middle game worlds were often little more than trading posts and side quests. I have no problem with much of the main plot being on worlds that I cannot return to.
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It does make sense to have something about planets that have not been previously encountered before. Otherwise it will probably end up like a restoration work rather than a flourishment of uncharted parts in systems of a Kotor game.