metadigital Posted September 25, 2006 Share Posted September 25, 2006 Why we're not immune to losing sleepLack of sleep could be worse for the body than we thought, at least if humans react to it in the same way as rats do Tarja Porkka-Heiskanen of the University of Helsinki, Finland, and her team discovered that rats seem to mount an immune response to sleep deprivation, producing molecules that ordinarily are associated with stress. This suggests that chronic sleep deprivation could lead to stress-related illness, such as heart disease, for example. Porkka-Heiskanen's team was studying how the brain triggers "recovery" sleep to overcome the effects of sleep loss. Their earlier work in rats had shown that levels of nitric oxide increase in the basal forebrain during periods of sleep deprivation and that this plays a role in prompting recovery sleep. They had also found that an enzyme called nitric oxide synthase (NOS) was responsible for jump-starting the production of nitric oxide. But where was the NOS enzyme coming from? Porkka-Hieskanen had expected that the NOS produced by the brain would be in a so-called "constitutive form", in other words, it would be made regardless of the need for it. Instead, her team found that the NOS was in an "inducible form" (iNOS) which is usually produced when the body mounts an immune response to stress (European Journal of Neuroscience, DOI: 10.1111/j.1460-9568.2006.05019.x). "This was a big surprise," says Porkka-Heiskanen. "It means that the body experiences sleep deprivation as some kind of hostile threat." The researchers also found that the rats began producing iNOS after being deprived of sleep for just 10 minutes. "So even short periods of sleep deprivation are able to create this reaction," says Porkka-Heiskanen. "If it becomes chronic, we are really putting a big strain on the body." OBSCVRVM PER OBSCVRIVS ET IGNOTVM PER IGNOTIVS OPVS ARTIFICEM PROBAT Link to comment Share on other sites More sharing options...
kirottu Posted September 25, 2006 Share Posted September 25, 2006 Go Porkka Go!!! This post is not to be enjoyed, discussed, or referenced on company time. Link to comment Share on other sites More sharing options...
Pope Posted September 25, 2006 Share Posted September 25, 2006 Tell me about it. I haven't had a decent night of sleep in 2 weeks, and having an exceptional high need for sleep, that makes Pope a really tired person today. I would sleep all day if only I could. Link to comment Share on other sites More sharing options...
astr0creep Posted September 25, 2006 Share Posted September 25, 2006 To many games to play. I'll sleep when I'm dead. http://entertainmentandbeyond.blogspot.com/ Link to comment Share on other sites More sharing options...
LoneWolf16 Posted September 25, 2006 Share Posted September 25, 2006 To many games to play. I'll sleep when I'm dead. <{POST_SNAPBACK}> Agreed! But if this has a granule of truth, that may not be as far off as you or I think... I had thought that some of nature's journeymen had made men and not made them well, for they imitated humanity so abominably. - Book of Counted Sorrows 'Cause I won't know the man that kills me and I don't know these men I kill but we all wind up on the same side 'cause ain't none of us doin' god's will. - Everlast Link to comment Share on other sites More sharing options...
Fenghuang Posted September 25, 2006 Share Posted September 25, 2006 I haven't slept all night, and I have things to do today. I never get enough sleep, and my health is excellent. RIP Link to comment Share on other sites More sharing options...
Arkan Posted September 25, 2006 Share Posted September 25, 2006 I love my sleep. I usually get six or seven hours a night, plus some nap time during the day...I love college. "Of course the people don't want war. But after all, it's the leaders of the country who determine the policy, and it's always a simple matter to drag the people along whether it's a democracy, a fascist dictatorship, or a parliament, or a communist dictatorship. Voice or no voice, the people can always be brought to the bidding of the leaders. That is easy. All you have to do is tell them they are being attacked, and denounce the pacifists for lack of patriotism, and exposing the country to greater danger." - Herman Goering at the Nuremberg trials "I have also been slowly coming to the realisation that knowledge and happiness are not necessarily coincident, and quite often mutually exclusive" - meta Link to comment Share on other sites More sharing options...
Xard Posted September 25, 2006 Share Posted September 25, 2006 Go Porkka Go!!! <{POST_SNAPBACK}> How can it be a no ob build. It has PROVEN effective. I dare you to show your builds and I will tear you apart in an arugment about how these builds will won them. - OverPowered Godzilla (OPG) Link to comment Share on other sites More sharing options...
Pidesco Posted September 25, 2006 Share Posted September 25, 2006 I haven't slept all night, and I have things to do today. I never get enough sleep, and my health is excellent. But you're like, sixteen. Everyone's healthy at sixteen unless they actively try to ruin their own health. "My hovercraft is full of eels!" - Hungarian touristI am Dan Quayle of the Romans.I want to tattoo a map of the Netherlands on my nether lands.Heja Sverige!!Everyone should cuffawkle more.The wrench is your friend. Link to comment Share on other sites More sharing options...
LadyCrimson Posted September 25, 2006 Share Posted September 25, 2006 who had only 4.2 hours sleep for 10 consecutive nights, hints at the dangers. Levels of a molecule related to iNOS called C-reactive protein were raised in the volunteers - a strong predictor of heart disease. I better buy some more life insurance, hubby's a gonner w/his sleep apnea stuff. “Things are as they are. Looking out into the universe at night, we make no comparisons between right and wrong stars, nor between well and badly arranged constellations.” – Alan Watts Link to comment Share on other sites More sharing options...
Diogo Ribeiro Posted September 25, 2006 Share Posted September 25, 2006 Get your sleep, peeps! <{POST_SNAPBACK}> Ah ah, you rat. Still trying here. Cheers. I told you my system was screwy - tried sleeping this afternoon, one hour and a half later was up again. Just can't for some reason. Headlight eyes. Game over man. Link to comment Share on other sites More sharing options...
Gfted1 Posted September 25, 2006 Share Posted September 25, 2006 I find I feel most rested when I get about 6-7 hours sleep. Any more then that and I wake up tired, any less and Im grouchy. "I'm your biggest fan, Ill follow you until you love me, Papa" Link to comment Share on other sites More sharing options...
metadigital Posted September 25, 2006 Author Share Posted September 25, 2006 I love sleep. Currently getting about 10-12 hours a night ... the best feeling is deciding in the morning that I don't feel like waking up just yet and rolling over for another hour or so of sleep ... :D interestingly, I decided to drink coffee last week (bought myself a new Bialetti Moka Express and some Lavazza), and I found it much harder to get up in the morning ... then again, it's not like i have to get up in the morning ... " OBSCVRVM PER OBSCVRIVS ET IGNOTVM PER IGNOTIVS OPVS ARTIFICEM PROBAT Link to comment Share on other sites More sharing options...
Dark_Raven Posted September 26, 2006 Share Posted September 26, 2006 6-7 hours of sleep is what I get. I could get more but I force myself out of bed, why waste the day. Hades was the life of the party. RIP You'll be missed. Link to comment Share on other sites More sharing options...
thepixiesrock Posted September 26, 2006 Share Posted September 26, 2006 I haven't slept all night, and I have things to do today. I never get enough sleep, and my health is excellent. <{POST_SNAPBACK}> But you're like, sixteen. Everyone's healthy at sixteen unless they actively try to ruin their own health. <{POST_SNAPBACK}> lol guilty. Lou Gutman, P.I.- It's like I'm not even trying anymore!http://theatomicdanger.iforumer.com/index....theatomicdangerOne billion b-balls dribbling simultaneously throughout the galaxy. One trillion b-balls being slam dunked through a hoop throughout the galaxy. I can feel every single b-ball that has ever existed at my fingertips. I can feel their collective knowledge channeling through my viens. Every jumpshot, every rebound and three-pointer, every layup, dunk, and free throw. I am there. Link to comment Share on other sites More sharing options...
the dude Posted September 26, 2006 Share Posted September 26, 2006 thanks for the links meta good info to know....and gives me more reason to not go for that masters degree.... " words are weightless here on earth because they're free Link to comment Share on other sites More sharing options...
Krookie Posted September 26, 2006 Share Posted September 26, 2006 I get like seven hours of sleep a night, and it doesn't really pose to much of a problem during the day. I just try to be in bed by 11, and fall asleep somewhere around 12. Of course, that doesn't always work because I've got my 360 in my room. Link to comment Share on other sites More sharing options...
Qazplm Posted September 26, 2006 Share Posted September 26, 2006 Sleep paralysis suck just had it. Link to comment Share on other sites More sharing options...
mkreku Posted September 26, 2006 Share Posted September 26, 2006 Well, I can tell none of you have been in the army, right? The first thing you learn is to fall asleep. Anywhere, anytime, any position. I can sleep standing. I (probably) need less than a minute to fall asleep if I want to sleep (this annoys the hell out of my girlfriend who has a much harder time to fall asleep). It's very practical. Usually I get 7-8 hours of sleep per night. Sometimes more, sometimes less. Swedes, go to: Spel2, for the latest game reviews in swedish! Link to comment Share on other sites More sharing options...
Pope Posted September 26, 2006 Share Posted September 26, 2006 Well, I can tell none of you have been in the army, right? The first thing you learn is to fall asleep. Anywhere, anytime, any position. I can sleep standing. I (probably) need less than a minute to fall asleep if I want to sleep (this annoys the hell out of my girlfriend who has a much harder time to fall asleep). It's very practical.<{POST_SNAPBACK}> So how do you do that? I'm one of those people that needs like at least an hour to fall asleep. I could sure use those l33t sleeping skillz. Link to comment Share on other sites More sharing options...
mkreku Posted September 26, 2006 Share Posted September 26, 2006 I acrtually don't know. The way they "taught" us that in the army was that the officers told us to "get sleep whenever you can" and then they forced us to work for weeks on end without proper sleep. You eventually got used to that weird rhythm and were able to fall asleep as soon as you got a free minute. Then an officer would come along ten minutes later and yell at you, and you'd be back at work. Repeat ad nauseum, and TADA, you've learnt how to fall asleep in no-time. I remember sleeping standing, leaned against a tree while on "guard duty". Hannibal and his elephant army could have walked past my guard sentry post. Swedes, go to: Spel2, for the latest game reviews in swedish! Link to comment Share on other sites More sharing options...
Tigranes Posted September 26, 2006 Share Posted September 26, 2006 Probably do a world of good for middle class buggers like me who can't sleep. Let's Play: Icewind Dale Ironman (Complete) Let's Play: Icewind Dale II Ironman (Complete) Let's Play: Divinity II (Complete) Let's Play: Baldur's Gate Trilogy Ironman - BG1 (Complete) Let's Play: Baldur's Gate Trilogy Ironman - BG2 (In Progress) Link to comment Share on other sites More sharing options...
thepixiesrock Posted September 26, 2006 Share Posted September 26, 2006 Get out! Just because he's hot- I mean, kind of good looking, doesn't mean I like him. Lou Gutman, P.I.- It's like I'm not even trying anymore!http://theatomicdanger.iforumer.com/index....theatomicdangerOne billion b-balls dribbling simultaneously throughout the galaxy. One trillion b-balls being slam dunked through a hoop throughout the galaxy. I can feel every single b-ball that has ever existed at my fingertips. I can feel their collective knowledge channeling through my viens. Every jumpshot, every rebound and three-pointer, every layup, dunk, and free throw. I am there. Link to comment Share on other sites More sharing options...
LadyCrimson Posted September 26, 2006 Share Posted September 26, 2006 I can fall asleep sitting on the floor behind the passenger seat of an automobile. It helps to be small. “Things are as they are. Looking out into the universe at night, we make no comparisons between right and wrong stars, nor between well and badly arranged constellations.” – Alan Watts Link to comment Share on other sites More sharing options...
kirottu Posted September 26, 2006 Share Posted September 26, 2006 I cannot sleep during daytime. Only exception is if I have been angry. Being angry is so mentally straining to me that I become very very tired. This post is not to be enjoyed, discussed, or referenced on company time. Link to comment Share on other sites More sharing options...
Recommended Posts
Create an account or sign in to comment
You need to be a member in order to leave a comment
Create an account
Sign up for a new account in our community. It's easy!
Register a new accountSign in
Already have an account? Sign in here.
Sign In Now