I played the game for a few hours (PC) and everything runs super smooth. It autodetected my 5870 and set everything to "ultra" and tbh, it looks good to me. Mind I dont have anything to compare it to but nothing is insulting my eyes. This is my first foray of any kind into the Fallout universe and with all this being new to me Im having a blast just wandering the areas scrounging through everything. I too saw the wildlife interacting with each other and there, just over the small hill, a running gun battle that I wasnt even involved in. I really like that the world does its own thing outside of my influence. Stopped playing last night after just rolling into Primm.
I think I screwed myself a bit on character creation. There was a screen that allowed the selection of two, I cant remember what they were called but some of the choices were "Good Natured" or "Small Frame", but it said on the top of the screen "choose two (or none)". I took the "or none" to mean I would be able to spend those points later but upon making level two I wasnt offered the opportunity. Oh well, going to play it out as is.