I'm lucky in that I've never had a really serious injury that needed serious meds. I'm not really prone to addiction either which is a blessing as most of my family is addicted to one thing or another. From gambling to alcohol or even harder stuff, you name it and I have an aunt, uncle, or cousin who just can't kick it.
I guess I have to kinda walk that back as I have been on several serious antidepressants and sleep meds but I wouldn't describe them as pleasant. There may have been a bit of euphoria when I took some sleeping pills but then for whatever reason couldn't go to sleep but it wasn't something I was ever keen to repeat
Sorry, I know that's not helpful