I'm waiting for a Sci-Fi game that's Sci-Fi, not Space Opera or a Flight Sim. Something that doesn't do FTL, energy weapons, sound in space, humanoid aliens, psychic powers, and a billion other things.
And I would prefer it be a good one with some narrative focus, choices, and RPG staples. There's technically a lot of games that are harder than Star Wars, but the narrative in them is all excuse plot. Red Faction, Killzone, etc.