You can basically replace Muslims with Guns in this sentence.
No you can't.
"When guns do this again and again and again and again and again and again and again and again and again and again and again the "Guns are not the problem" argument fails to hold water."
You quite literally can. As Barothmuk already mentioned, we just had the planned parenthood shooting. We have mass shootings with alarming regularity in the US, and yet very few are tied to Islam.
It's easy to blame guns, or blame a religion, for this type of senseless violence. But I fail to see how that will help us move forward and prevent them in the future, unless you plan on banning guns and religion.