Hard to say.
I liked Bloodlines because it was a universe I was completely unfamiliar with.
I like KOTOR 2 because lets me play in a Universe that I like and am familiar with.
Bloodlines easily has one of the coolest missions I have ever seen, in ANY game.
I thought Bloodlines got off to a really, really good start....but the ending was perhaps a bit too combat oriented (although aren't all RPG endings like this now?).
Given my experience in Bloodlines, I would still pay $50 for the game (providing of course I didn't actually know the details of the plot, but just knew how much fun I would have in the game). For what it's worth :\
No drow, nor orcs. Just Vamps, the associated other dark creatures (ghouls, werewolves), and cattle---errr...humans.