I've been getting pretty hyped about Gray Matter. It's the first big Jane Jensen game after GK3, and from what I've seen & read it reminds me a lot of The longest journey, with a setting combining magic in a high-tech future Earth. The main character (female, of course) seems pretty interesting as well.
Maybe it will be the next big adventure game that revitalizes the genre and puts it back on the radar after years of mediocrity. Hopefully it is released this year.
For the rest, I'm looking forward to Drakensang's Phileasson's expansion. Supposedly it's only 10 hours long, but one will be able to import the party from River of Time & visit a legendary location in DSA lore, similar to D&D's Myth Drannor.