I like the color and theme of the UI but I do think you could tweak it a little
1. Cut off the UI when using widescreen resolutions, it helps to make it more minimalistic
2. Remove the journal/inventory part of the UI, most players are going to use hotkeys and removing that part makes more room for the portraits ect.
3. Make the event menu full screen covering the UI, it's a small adjustment but it incresses the players immersion and reduces the distraction of the UI, helping the player to focus on the chocies
Also how are you handleing high resolutions? In isometric games like Baldur's Gate and The Temple of Elemental Evil, when you incress the resolution the camera zooms out, making it feel more like your controlling ants in a maze than adventures in a dungeon.