Alright, having blasted through the first hour or two I have to say the game looks like its everything I expected it to be, and my expectations were high. The story seems quite interesting, the combat is polished up and is much faster and smoother(it was quite clunky in ME1) and the general mood of the setting is fantastic. I just wandered around Omega for ages just looking at stuff and enjoying the scenery.
My Shep is hawter than yous. And for some reason BioWare has disabled the screenshot function in ME2 so you have to use Fraps. There is a screenshot folder and everything, they've just disabled it in the code.