I will say, something I've always wanted to try out is something set to the Arabian Nights style background. The closest I've seen is TSR's old Al-Quadim, and I could never persuade my gaming group to try it out.
It would be interesting to see what Obsidian might do if they overloaded on old Sinbad movies and the Thief of Bagdad, sprinkle in a bunch more from the 1,001 nights, and see what emerged.