December 11, 20223 yr Because genetics always interested me... https://www.bbc.com/news/health-63859184 A teenage girl's incurable cancer has been cleared from her body in the first use of a revolutionary new type of medicine. All other treatments for Alyssa's leukaemia had failed. So doctors at Great Ormond Street Hospital used "base editing" to perform a feat of biological engineering to build her a new living drug. Six months later the cancer is undetectable, but Alyssa is still being monitored in case it comes back. ... They started with healthy T-cells that came from a donor and set about modifying them. The first base edit disabled the T-cells targeting mechanism so they would not assault Alyssa's body The second removed a chemical marking, called CD7, which is on all T-cells The third edit was an invisibility cloak that prevented the cells being killed by a chemotherapy drug The final stage of genetic modification instructed the T-cells to go hunting for anything with the CD7 marking on it so that it would destroy every T-cell in her body - including the cancerous ones. That's why this marking has to be removed from the therapy - otherwise it would just destroy itself. If the therapy works, Alyssa's immune system - including T-cells - will be rebuilt with the second bone-marrow transplant. ... It may have been a fluke, but maybe they're on to something. While Mama Merkel's billions swayed Biontech to change their line of mRNA research from cancer to covid, I do believe the "reliable" cure for cancer is through targeting the cells with a scalpel approach rather than the sledgehammer/tnt approach of chemo and radiation, trying to kill the patient as much as possible and hope the cancer cells dies before the patient. “He who joyfully marches to music in rank and file has already earned my contempt. He has been given a large brain by mistake, since for him the spinal cord would surely suffice.” - Albert Einstein
December 11, 20223 yr This Alloy Is The Toughest Known Material on Earth, And It Gets Tougher in The Cold : ScienceAlert
December 12, 20223 yr Fusion energy breakthrough by US scientists boosts clean power hopes | Ars Technica
December 12, 20223 yr 15 minutes ago, Gfted1 said: Fusion energy breakthrough by US scientists boosts clean power hopes | Ars Technica Hah, was just reading about it. that part about some measuring devices being broken during the test are bit worrying I'm the enemy, 'cause I like to think, I like to read. I'm into freedom of speech, and freedom of choice. I'm the kinda guy that likes to sit in a greasy spoon and wonder, "Gee, should I have the T-bone steak or the jumbo rack of barbecue ribs with the side-order of gravy fries?" I want high cholesterol! I wanna eat bacon, and butter, and buckets of cheese, okay?! I wanna smoke a Cuban cigar the size of Cincinnati in the non-smoking section! I wanna run naked through the street, with green Jell-O all over my body, reading Playboy magazine. Why? Because I suddenly may feel the need to, okay, pal? I've SEEN the future. Do you know what it is? It's a 47-year-old virgin sitting around in his beige pajamas, drinking a banana-broccoli shake, singing "I'm an Oscar Meyer Wiene"
December 12, 20223 yr It's only 20 years from now! "only when you no-life you can exist forever, because what does not live cannot die."
December 12, 20223 yr I wish I'm the enemy, 'cause I like to think, I like to read. I'm into freedom of speech, and freedom of choice. I'm the kinda guy that likes to sit in a greasy spoon and wonder, "Gee, should I have the T-bone steak or the jumbo rack of barbecue ribs with the side-order of gravy fries?" I want high cholesterol! I wanna eat bacon, and butter, and buckets of cheese, okay?! I wanna smoke a Cuban cigar the size of Cincinnati in the non-smoking section! I wanna run naked through the street, with green Jell-O all over my body, reading Playboy magazine. Why? Because I suddenly may feel the need to, okay, pal? I've SEEN the future. Do you know what it is? It's a 47-year-old virgin sitting around in his beige pajamas, drinking a banana-broccoli shake, singing "I'm an Oscar Meyer Wiene"
December 12, 20223 yr 21 minutes ago, Lexx said: It's only 20 years from now! You remind me of Walsingham. Maybe they should give up since it didnt work the first time? I hope I live to see it but at least my daughter will benefit. w00t!
December 12, 20223 yr I also wish them to succeed, but news like this are posted so often now, the pessimist in me can't take them serious anymore. "only when you no-life you can exist forever, because what does not live cannot die."
December 12, 20223 yr Civilization, in fact, grows more and more maudlin and hysterical; especially under democracy it tends to degenerate into a mere combat of crazes; the whole aim of practical politics is to keep the populace alarmed (and hence clamorous to be led to safety) by menacing it with an endless series of hobgoblins, most of them imaginary. - H.L. Mencken
December 12, 20223 yr love me some snatch I'm the enemy, 'cause I like to think, I like to read. I'm into freedom of speech, and freedom of choice. I'm the kinda guy that likes to sit in a greasy spoon and wonder, "Gee, should I have the T-bone steak or the jumbo rack of barbecue ribs with the side-order of gravy fries?" I want high cholesterol! I wanna eat bacon, and butter, and buckets of cheese, okay?! I wanna smoke a Cuban cigar the size of Cincinnati in the non-smoking section! I wanna run naked through the street, with green Jell-O all over my body, reading Playboy magazine. Why? Because I suddenly may feel the need to, okay, pal? I've SEEN the future. Do you know what it is? It's a 47-year-old virgin sitting around in his beige pajamas, drinking a banana-broccoli shake, singing "I'm an Oscar Meyer Wiene"
December 13, 20223 yr 8 hours ago, Chilloutman said: love me some snatch It's such a quotable film Civilization, in fact, grows more and more maudlin and hysterical; especially under democracy it tends to degenerate into a mere combat of crazes; the whole aim of practical politics is to keep the populace alarmed (and hence clamorous to be led to safety) by menacing it with an endless series of hobgoblins, most of them imaginary. - H.L. Mencken
December 17, 20223 yr Staying on theme; Civilization, in fact, grows more and more maudlin and hysterical; especially under democracy it tends to degenerate into a mere combat of crazes; the whole aim of practical politics is to keep the populace alarmed (and hence clamorous to be led to safety) by menacing it with an endless series of hobgoblins, most of them imaginary. - H.L. Mencken
December 27, 20223 yr U.S. Dept. of Energy Plasma Discovery Unravels Odd Solar Phenomenon, Offers Clues to Cosmic Mysteries - The Debrief
December 29, 20223 yr Successful hypothermia in nonhuman primate paves the way for future application in human torpor during spaceflight "It has just been discovered that research causes cancer in rats."
April 12, 20232 yr Europe is about to launch one of its most ambitious missions ever | Ars Technica 8 year journey!
April 13, 20232 yr 53 minutes ago, Gfted1 said: Europe is about to launch one of its most ambitious missions ever | Ars Technica 8 year journey! 'JUICE'... 😁 Only 1 year delay, not bad for a project of that scope I guess 🤔 “He who joyfully marches to music in rank and file has already earned my contempt. He has been given a large brain by mistake, since for him the spinal cord would surely suffice.” - Albert Einstein
April 13, 20232 yr On 12/17/2022 at 3:16 PM, Azdeus said: Staying on theme; at 1:37 is mentioned the narrator sees visual flash from fusion. ... maybe everything else is complete legit, and perhaps the lightshow is for the tourists, but is no way you should be seeing anything. if visual light is escaping their containment, then so too is rather extreme x-ray energy. admitted we did not watch further 'cause we had already read articles 'bout what helion is doing. am actual optimistic 'bout helion particular after the JASON review, but am thinking some o' what o' going on in the video is a glorified flea circus to generate funding. HA! Good Fun! "If there be time to expose through discussion the falsehood and fallacies, to avert the evil by the processes of education, the remedy to be applied is more speech, not enforced silence."Justice Louis Brandeis, Concurring, Whitney v. California, 274 U.S. 357 (1927) "Im indifferent to almost any murder as long as it doesn't affect me or mine."--Gfted1 (September 30, 2019)
April 13, 20232 yr 12 hours ago, Gromnir said: at 1:37 is mentioned the narrator sees visual flash from fusion. ... maybe everything else is complete legit, and perhaps the lightshow is for the tourists, but is no way you should be seeing anything. if visual light is escaping their containment, then so too is rather extreme x-ray energy. admitted we did not watch further 'cause we had already read articles 'bout what helion is doing. am actual optimistic 'bout helion particular after the JASON review, but am thinking some o' what o' going on in the video is a glorified flea circus to generate funding. HA! Good Fun! True, but it could be from cameras inside the containment, atleast that is how I interpreted it. Civilization, in fact, grows more and more maudlin and hysterical; especially under democracy it tends to degenerate into a mere combat of crazes; the whole aim of practical politics is to keep the populace alarmed (and hence clamorous to be led to safety) by menacing it with an endless series of hobgoblins, most of them imaginary. - H.L. Mencken
April 14, 20232 yr Green light go: SpaceX receives a launch license from the FAA for Starship | Ars Technica
April 15, 20232 yr The current launch time is set for monday. Let's hope there won't be any scrubbing. "only when you no-life you can exist forever, because what does not live cannot die."
April 19, 20232 yr Quantum light source goes fully on-chip, bringing scalability to the quantum cloud (interestingengineering.com)
April 29, 20232 yr ChatGPT-AI, Google tech, give voice to Boston Dynamics’ robot dog Spot (interestingengineering.com) Europe's JUICE Jupiter probe suffers antenna glitch in deep space | Space Hopefully they can jiggle it loose.
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