The introduction to ME2 also qualifies.
You get spaced, your suits integrity is compromised, and you suffocate (Long term hypoxia will give you massive brain damage), you fall down through the atmosphere of a planet and hit the ground, even if Shepard isn't a wet spot on the ground by now, the ammonia atmosphere will likely start melting what is left on the ground while people are looking for the body. But let's set that tiny niggle aside, the temperature on that planet is freezing, even if Shepards brain wasn't splattered the freezing of Shepards brain will likely turn it into mush.
Anyway, you wake up, you've got a bit of scarring on your face...