The thing that bothered me the most about the voice acting was how they had these one-liners that were dependent on where you were in the main quest line. All of a sudden all the NCR soldiers started saying the exact same thing, for example, "I heard we took back Nelson, maybe we can win this war after all". But what was weird, to me, was that every soldier said the exact same thing, despite having different voice actors.
I could click on a female solider and she'd say her main story one-liner, then I'd click on a male soldier and he'd say the exact same thing, word for word, as the female soldier, but with a different voice. When they went through the trouble of having the different voice actors record all those one liners, couldn't they have put a note on the one-liner manuscript saying "improvise around this"? Just let different people word it slightly differently, like we do in real life. Hearing everyone say the exact same sentence, over and over, was very creepy.