I loved MDK 2.
I loved those 15 minutes of Morrowind when a friend o' mine got his plate mailed, two handed axed ass handed to him by a naked, barehanded barbarian. And oh yes, poking attack animation with an axe. Hilarious.
But the dialogue is separated from other aspects of gameplay. Talking professional doesn't force me to play a (literal) sneaking backstabber, I can go shotgun blazing or grenade lobbing if I'm so inclined.
"Sis"? Are you saying I'll get to "enjoy" some pseudo-Japanese "Onii-chan"-style fetishisation of brother-sister incest?
Dunno about incest, but there was a character mentioned who calls Mike 'bro', could be her. Or was that a guy?