I tend to think of technology as another form of "evolution". Granted, regular biological evolution is no longer a factor in the development of our species, but where before it took thousands of years and the death of a lot of "unfit" individuals to eradicate a defective gene, it appears that soon (real soon!) we will be able to do just that instantly and most importantly, in live individuals. The same goes for those new robotic prosthetics that are being developed. That's the substitute for the organic regeneration that nature didn't grant us.
That said, I'm all for genetic manipulation. I think it's absurd not to take advantage of all the benefits that genetics could provide just because it won't be for everybody.