The Top 100 Videogame Villains according to IGN.
It's an all round mixed bag. I mean ...Dagoth Ur, seriously? The most memorable Morrowind NPC was that House Hlaalu dude who made you take your pants off. And ineffectuals like Malak and Saren rate relatively high, as does Harbinger who is a total non-entity in ME2. What do you make of it? And while we're at it, who would you rate as an effective videogame antagonist?
For me personally:
Anachronox - Vendelin Detta
Fallout - The Master
Grand Theft Auto 4 -
Grim Fandango - Domino Hurley
Jade Empire -
Splinter Cell: Pandora Tomorrow - Norman Soth (might need to explain this one)
Star Wars: Knights of the Old Republic 2 - The Sith Lords -
System Shock 2 - SHODAN
Tales of Vesperia -
Thief II: The Metal Age - Karras
I've had to spoiler tag some because I'm not sure when the expiration date for these spoilers is...