No, not really.
Take myself and Llyranor's latest game, 2v2v2v2v2v2 (I think , there might be more 2's), on epic speed. I'm playing the finantial/expansive English (more money, less health problems) while Llyranor is playing the philisophical/creative Germans (more great people, more culture).
Off the bat our tactics were for Llyranor to start producing a lot of great people points to get an advantage in production late on into the game with a host of super-specalists and other stuff, but to do that, we needed the parthanon, luckily we started off with marble. Teching to polytheism via mystisism, Lly had to build the Parthanon as fast as posible, which meant only creating a bare-bones of a civ. Hence we had to cooporate VERY closely to assure the wonder was built, and it came very close a few times, with barbarians raiding the city and cutting off our resorces, while also trying to stop our opponents overexpanding on the land we would need later. To this end I even built a settler and gave it to Llyranor so he could build a 'plug city' to stop another nation expanding across land. Then we got another scare when it looked like alexander might build a city between us, cutting off the supply line I had built between our two nations. Trying to balance diplomacy between the other civilizations was a big issue too, and we even got bullied out of some technology at some point because we couldn't afford to go to war. Very cool game.
The fact that you're really playing with another human, which means actual strategy, plus the fact that on epic speed, every desision becomes important and long-term.