I have a similar problem, but the game does not crash, but hangs tightly (you can only delete the process in the task manager). And this is observed only on saves made before 0.3, there are no problems on the new game (at least for 1 hour the game never hung up).
Upd.
After crawling around the forum, I decided to test hypothesis about the number of save slots. I deleted all autosaves and left 5 pieces of the necessary main ones. After launching, the game still hung several times, and then it work fine. For at least the last 4 hours, there hasn't been a single hang.
Upd2.
Several days of testing have shown that the hypothesis about the number of slots is untenable. The game continues to hang and no dependency of hangups on anything could be detected. Moreover, it can sometimes work normally for several hours, and sometimes freezes occur in series just a few seconds after loading the save.