Funny, I always bought Sapphire cards before, and this time I got a 4850 from another manufacturer. Had tons of problems with games crashing, Vista and disk getting corrupted, although I think Vista and disk controller had something to do with it also, but perhaps only as effect not cause. Anyway, finally replaced it with an XFX GTS250, no problems so far, although the only game I've been playing is ETW and not that much.