I know I felt pretty bad when that French scientist chick in System Shock 2 got killed in the hangar due to my mistake.
Delacroix?
It does kind of suck when people die because of your mistakes, but usually you can avoid it or it's just expandable RTS sprite-people.
Yes, Delacroix. And no, the character really grew on me. And just about when I was to meet her in person, she dies. That sucked.