Glitchy vats (mentioned in another preview), stuttering framerate, bad pathfinding, people attacking you just because you touch an unimportant object flagged as the property of one particular faction.
Other than the 'glitchy vats' bit, I didn't really run into any of those problems you mentioned. Not arguing of their existence of course.
Well they didn't really hamper my enjoyment of Fallout 3, so I doubt they'll make me somehow mysteriously hate Fallout : New Vegas.
That is, of course, assuming Obsidian doesn't introduce other (more serious) bugs, but for now there's no indication of such thing.