If you've already been to deck of many things Missile Gloves are even better than Necklace of fireball, no worries about Aoe hitting vela and more dmg per cast, pretty sure both can be stolen for free (other one in crookspur) if your mechanics is high enough and you have slippers (only item you have to buy from deck) and once you have 2 you can "recharge" them for free in stash.
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Amra does trigger on barrels (or ranger pet) no need for fire blight)
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Death's runes can't be extended, it's a temporary aura ON the corpses, similar to cipher effects on foe.
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As Kaylon stated you only need immunity from afflictions for least unstable coil, then it won't be overwritten unless you use it again (can easily be prevented by unequipping saving and reloading, which will change the name of the buff but will weaken some effects of the inspirations like robust)
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Darkest before dawn is not risky at all unless you have 3 injuries, it will just knock you out if you overdo self dmg (but you can do it real controlled with missile gloves), just keep in mind its not wise to get dmg reduction before you have your deltros extended)
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At least on several different chars I tested you can also get shadow form by double click equipping slippers from inventory, weirdly enough Kaylon said it doesn't work for him, so idk if there is a hidden requirement which I happened to have on seevral chars I tested it with, otherwise barrels will do the trick.
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For reforge the flesh you will get permanent recovery even if you got rid of paralyze, so you also have to weapon switch save reload and weapon switch again to get rid of that.
Keep in mind unless you are a black jack or barbarian (sof extended bloodlust) you won't ever be able to weapon switch in combat only switch save reload switch will make recovery possible, also keep in mind getting arcane dampened while having reforge means you might as well be dead even tho the enemies will most likely not be able to kill you, but you won't be able to do anything and ofc can't save and reload unless you wanna do the old cheese obsidians tcs system and just load another game.