I like to be able to customise as much as possible, and it will be a shame not to be able to choose gender, certainly. If you're going to close off the choice of playing as a female character, in order to give greater depth to the male character's story, then the story really has to deliver in order to compensate. I'm hopeful that it will deliver.
Some of the unofficial info leaked in the Game Informer article suggested that you'd be choosing your 'manner' in dialogue trees (aggressive, cautious etc.) rather than reading and selecting actual lines of dialogue in a Kotor2 style. If that's the case, then good ol' Mike's every word will be recorded by a voice actor and there can't really be any choice of voice set, I guess.