I thought the devs said that such an arrangement wasn't feasible. However, if it's possible, I don't know why we shouldn't. I guess I spoke too quickly.
On the other hand, the things that most intrigued me about the game transcended the story. I liked the faction, epithet, and alignment system. I liked the idea of using floating text with quick blurbs to convey set some of the tone. I liked the idea of an expanded and more robust clerical domain system that what we've seen in CRPGs to date.
Those things are part of the game. The story uses them, but I didn't think the engine could handle all of these things. If I'm wrong, which happens a lot, then I'd love to see Jefferson. In fact, if I'm wrong, I can think of no better meal than crow.