It's a good idea, but you have to be careful of just what you engineer out. Who knows what might drive us into an evolutionary dead end if you start taking short cuts without any consideration for the consequences.
Health tweaks are good, adjusting for the possibility of outer space travel or easier colonisation of not-perfect terrestrial worlds (if we ever get there). Then again, there's going to be the balance of genetically engineered bioware along with cybernetic interfaces and implanted technologies. Heh, now I'm inspired to go running for the old Shadowrun books.
Shall we all start listing the joys of transhumanism right now?