Paraphrasing Dan Spitzley:
So yeah, I would like to see ScottE working on a new Fallout game, or read some dialog by Huggies, his lines in van Buren are awesome, or poke Sawyer and Fergus a bit more ("That's not canon! You need more sleep!") , even if it was a handheld Fallout Advance: Tactics game, or a spiritual successor Bioshock style.
But the reality is if they tried to make a RPG then it had to be a Next-Gen simplified game for consoles, since it's all everyone can do these days, and that is already covered. And Bethsoft will stick with the Fallout games for themselves an