Multiclassing feels more powerful early game, where as single classes, especially casters feel way more powerful in the late game.
Xoti for example. I made her a pure priest solely to buff and heal. Around level 10 she wasn't as useful anymore and I regret not going Priest/Monk to have the Swift Flurry so she can do more damage. At level 16 I got access to Spark the Souls of the Righteous, which is such a hilariously powerful spell that even non-empowered ended all fights within 10 seconds.
(For those that don't know, it places an AoE on every ally/summon it hits that ticks for 15-25/*30-50 damage in an AoE every 3 seconds for 30/*45?60? seconds.)
You hit that on your 2 melee and 3-6 summoned minions, suddenly everything around you just dies.
Imho, Multiclassing is more powerful for longer/sustained fights especially with melees and creates more powerful tanks, where as single class is stronger for casters and shorter fights. Then again, the empowered spells will likely make every fight a short fight, so that point is relatively moot.