Oooh found this @ planet vampire
Performance Increase
-add: -heapsize xxxxxx after the targetline in the shortcut for bloodlines.Where xxxxxx stands for half of your RAM in kb.So if you have 512 RAM the shortcut target line should look like this:"C:\Program Files\Activision .... blah blah blah\vampire.exe" -heapsize 250000
To enable the console too just make it look like this:
"C:\Program Files\Activision .... blah blah blah\vampire.exe" -console -heapsize 250000
And if you were wondering,yes you have to add those spaces in between.
-When you run the game,before you select a new game or load a saved game, hit the "~" key to bring up console, and type:autosave_on 0
That will disable the autosave and increase the loading speed.
-After that type:particles_enable_precipitaion 0
to disable the rain.
-Open the cfg folder and file in the Vampire folder and:
1.change: rate to "25000"
2.change: dsp_dist_max to "440" (you don't have to do this one,but try it and see if you need the change)
-Disable antivirus software
-Change the paging file size so that the number you typed in + your Ram size equal 2048mb.