Wanderer's Edition actually contains all those mods and it actually works surprisingly well and fundamentally changes the way you play Fallout 3 (for the better in my estimation, but it's definitely a matter of taste) pistols become useful, shotgun shells become precious resources, most of the skills become more useful and you can't specialize in more than a few, you're no longer invincible (you have to run and use tactics with most of the battles, and the dart gun becomes 1000x more useful), healing becomes tougher (there's an optional "triage" mod that requires you to have surgical tubing in order to apply stims to limbs), sprint and slo-mo add some tactical elements, and there's even a bit of variety added in PC backgrounds (I'm playing as a ghoul, which means feral ghouls are neutral to me and environmental radiation slowly heals me and reduces my rad count drastically, but there are other backgrounds that change up where you start, your equipment, modifiers to your skills, etc.) that really add something to the game up until the point at which you start the main questline and all of a sudden you're from the Vault (F3 being what it is, however, you can delay that for a long, long time)
It's actually one of the more successful full-game conversions I've played. I'm wondering if Sawyer has played it, since it seems like it'd be up his alley. There are some balance issues, but nothing particularly egregious.