Well, my attempt (Path of the Damned, Trial of Iron, Expert) was short-lived (har!). I rolled my dwarf monk Rude E. Kegbiscuit knowing relatively nothing about the mechanics. I breezed through what I assumed were "tutorial"-class fights, then got myself in a pickle. I thought I was doing fine then BAM! Game over.
The game really should have a post-mortem and/or graveyard (roster of deceased characters) to fully support an ironman style. It'd be nice to review what done you in (the last X lines of the combat log could help here).
Now I'll just go back to my normal, iron-free, non-expert gameplay experience.