After watching all the video I could find on AP, I'm pretty firmly in the "looks like alot of the mechanics are from Mass Effect, but don't think that's necessarily a bad thing" camp.
Looks like it's got alot of positive differences going for it as well to me though.
Between this, Dragon Age, and Forza 3 it looks like I'll have most of my free time covered from October - December assuming there's no more delays.
I've been playing cRPGs pretty avidly since Wizardry and the SSI gold boxes. Based on the available footage I've been able to find so far, I see alot more common elements in AP from ME than VtM:BL or VtM:R personally.
The simularity in shooting mechanics probably is attributable to both games being Unreal 3 driven. The dialog mechanic, the ability selection, and the character development seem to be cases of emulating something that seemed to have worked pretty well in ME, IMO.
I really have no problem with that. Sounds like the innovation will be in the gestalt of this cinematic approach merged with a slightly more adult aesthetic and hopefully more true role playing options (ie: more freedom and significant consequences in choices and story arcs that aren't quite so much on rails)
Just my .02 based upon the gameplay, trailer, dev diary, and interview vids though.