I didn't know this was a mechanic, but I ran out of water and was struggling to find some, then I was notified I could no longer see my trail makers. Must be from dehydration. Found water, markers didn't come back. Slept the night, markers still not back. Checked my map, clicked on trail markers and the game crashed 

Had this same thing happen but i wasn't dehydrated before it happened,

Clicking on Trail Markers always crashes me.

Same here, it is a known bug. Just don't click at it.

never had that happen,  i play on xbox,  when the markers vanish i toggle them off and back on again.  seems to bring them back for me.