Depends what you're used to, certainly. Anything you become proficient enough in will feel like second nature. Btw, you can't just plug in the 360 controller into the PC as was said, since most PC games don't support it. I have software which lets you do that, but it has its own set of issues, chief among them that the aiming support in the game is for a mouse, not controller, so you can't aim very well.