Companions seem to trip and die. I had Nyoka just fall down dead from walking. Unfortunately the only workaround is reloading and making sure that you save a lot.
Tripping and dieing is common from what i have seen. It has happened multiple times to my companions. The only workaround i have found is going back to an earlier save and generally that fixes the issues.
Every time i start a new game, after getting past the first 2 marauder groups the game crashes with an "Out of Memory error". I have tried every graphics option, restarting, old and new video drivers, different resolutions, and every display mode (windowed, borderless, fullscreen).
Specs
Win 10, 5960x, 64gb ram, 1080ti GPU.