Sooo, I am in a tricky situation and I'd like some experienced players' insight. Spoilers ahead and all that.
So, I visited Ondra's Gift before Brackenbury District and I reached the Vailian Trading Company. My aim was to get Pallegina. I got the quest "At All Costs". I have no interaction with House Doemenel up to this point. I've found that letter about the jewel theft but I have not showed it to anyone yet. Well, I went back to Copperlane District, at the inn, and now I know I will encounter Danna. I want to kill her, preferably in the Inn, I know I will fight her angry boyfriend later, I will also kill Verzano for putting me into this mess later, most likely. The problem is, I will get negative reputation with the Doemenels, does this mean I will not be able to visit them in "neutral" terms, do their first quest "A Two Story Job"? I want to open up their merchant, obviously. And I know there is also another side quest they give, not to mention the 2nd main quest to get an invitation to the Animancy hearings. Will killing Danna Doemenel or even opposing her block my access to all these? Or do I still have my chance, by using that letter I found? Actually, what if I kill Danna and also give the letter to the rival house of the Doemenels, do I still have the option to join the Doemenels' side then?