There are now more and more people using computers with multiple monitors, especially because of the proven benefits to productivity and to ease of use to the user.
However, the gaming industry often treats multiple monitor support as an afterthought, if they even support it at all. This is of course understandable, especially when multiple monitors were first starting to become popular. Why waste developmental resources to design and create something that most users could (or would) never use? However, those gamers that did have multiple monitors didn't want to waste the extra screen they had, which lead to demanding (or using workarounds) to play games in windowed mode, so they they could easily switch to an internet browser or another program in the middle of their game to do something else and multitask. They could be chatting with friends on an IM program, or have the other screen open to an FAQ of they game they are currently playing.
However, there are some genre of games that have used multiple monitors to great effect. Flight simulators, racing games, even some FPS that use extra monitors to increase the field of view of the player. RTS games like Supreme Commander or World in Conflict use the secondary monitor as an additional and larger mini-map to help the player keep track of their units on the map.
So here's the question. Do you have any ideas for how role playing games, isometric, full 3d or otherwise could incorporate multiple monitor support in a way that could benefit the player? Or are RPGs as a genre a type of game that doesn't really benefit from multiple monitors in any way?