If we get off the rock, where are we going to go? The closest star is over 4 light years away. And then we'd have to hope that there's a planet there that is habitable. Alpha Centauri A is at least the right type of star...though there's that annoying Alpha Centauri B that will likely screw things up. Not sure how many habitable planets a twin star system could have.
Proxima Centauri is a little closer, but way too hot.
We better figure out how to start warping Space Time. But to be honest, I think we'd have to learn how to terraform a planet like Venus first. This way if we go somewhere and there's a planet that is close to what we need, we can at least do something with it.
I don't see us colonizing other worlds anytime soon though. At best maybe using resources from off our planet.
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Mars could be colonized.
Space habitats could work (we'd need stronger materials and ways to deflect impacts though)
The astroid belt between mars and jupiter most likely has enough resources to do darn near anything in it.
We NEED to get into space.. and soon.