A few spelling mistakes would be understandable if Obsidian were undertaking the fifth grade again. In a professional game product, in this day and age, it's unforgivable and also emblematic of the lack of common education in our US citizenry.
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While I have noticed some places in the dialog where there have been mistakes made, let's not forget that there are literally hundreds of lines of dialog, if not thousands. Given that, I would expect mistakes to creep in.