How on gods green earth do I use potions? I put one in my quick bar. I can't pre buff with it because it says I must be in combat. I can't use it in combat because I click on it and nothing happens. What am I missing? Is this a bug of some sort I'm unaware of? A potion or two would really help against these ogres in the Endless Paths...

You have to click on it, in combat, and wait a second or two for it to get used. At least, that's how it works in my game. I have noticed that on occasion I have to click on it again because they went back to attacking an enemy or something.