To replicate, go into stealth mode outside ogre cave and search the skeleton. right click on ring to bring up item description, close the loot box to see whole description. Now unable to close item description. Item description will still be on screen even when reloading a game.

 

This doesn't happen in other instances.

http://forums.obsidian.net/topic/70483-435-that-item-description-bug-i-was-talking-about/?hl=%2Bitem+%2Bdescription ?

I've encountered this bug in build 435. It happened exactly twice, both when I tried to check item's description in loot window. At the first time it was a crossbow, second item was a belt (both found in spiders/ogre cave). Description window was persistent so I had to quit to main menu and then load again.