Not sure if this will actually be an issue in practice, but every time I press X to talk to someone the weapon is unholstered which is a little character breaking. I've tried reloading, restarting the game, and restarting Windows. Playing with an Xbox controller in Windows 10 in the Xbox beta app.

Until there's a fix, I use antimicro and assign the E key to LeftThumbstick press and use that to talk to people

I have the same problem on Xbox. Mainly with the randomers like "citizen" but it doesn't happen so much on people who have a proper convo with you. 

There's another thread about holstering