I've just reinstalled this game to eliminate a possible corrupt install but I still have a serious problem. I've never been able to play TOW on this new 4k monitor. The game did play okay on an old 5k>4k Dell monitor but that one has been discarded. The issue shows right from the start screen onwards in the menus. Click-boxes are displaced from the text about 90mm in a SE direction. That means I must find the hot-spot a long way away from the actual menu text. Most menu items are not clickable because the hot-spots are off-screen. I went as far as I could to see the extent of this problem and every menu item behaved the same. The new monitor is a ASUS ROG SWIFT PG27UQ. The old monitor was a 5k Dell run at 4k resolution.
I've run other Bethesda games okay including Fallout New Vegas - none show this problem. Only The Outer Worlds does it. I've spent several days researching this and trying various approaches. None have helped.