I've actually just registered to add to this thread.
I've been a big fan of Obsidian for a while now - being one of the minority who preferred KOTOR2 to the first - and picked up Alpha Protocol two weeks ago. I have hardly stopped playing it. As Nonek says, it's everything a game should be; just beginning my third playthrough.
I'm on Xbox and don't seem to have encountered the glitches so far - except for reloaded checkpoints getting rid of enemies, and that sort of thing. Nothing too much to worry about, doesn't ruin the game for me at all. Would prefer some more customisation of Thorton, but again, not a huge worry. Overall, I can't beleive the bad press the game's received (maybe I'm looking for different things in a game than others?).