The problem with a sequel like this is two things
1. It can go completely wrong and end up like DX: Invisible War
2. Or it can improve things but take away a lot of RPG elements like Mass Effect 2
The problem is I liked being universally combat capable in Mass Effect 2, since as a Soldier I could be just as proficient with a sniper rifle as I could with an AR, shotgun, or pistol, etc. etc.
As it is here, you have to dump points into weapon skills in order to not suck with them. So you trade universal combat over stat RPG based combat, etc. etc.
Honestly I'm on the fence both ways. Regardless, I'd like greater customization of Thorton, preferably full face and armor look customs, and better visual weapon upgrades.
Ironically I hated how every other weapon I got in Mass Effect 1 was a reskin with the same look. The designers did the same here yet when ME2 came out there was a vastly diminished amount of weapons available and I suddenly missed all the guns from ME1. So as far as I'm concerned, keep the weapon reskins in, but perhaps put in more new looks rather than a new paint job for every single one.