In my opinion, one should avoid the "Let's talk about something else" option in favour of an "[Other topics]" option. The latter would instantly bring up dialogue choices. When questioning a character, it is annoying to listen to the line "What would you like to talk about?" multiple times before exhausting them of useful information. How many times do players click on "Let's talk about something else," listen to or skip "What would you like to talk about?," only to discover that all questions have been asked? This problem could be mitigated by remvoving the dialogue on such options altogether. It is also important to give clear feedback to a player when they have exhausted a particular line of questioning before. Too few RPGs handle these matters well.