I had one crash on my initial play through, which I completed yesterday. I have no idea, expect it was just a memory leak because it was after many hours of playing in one session.
The only gotcha I've found yet, is it seems over too quick for the full price. Yes, I yearn for a large DLC, and maybe on the play through I start today, I'll try to do all the bounty quests and exploration before worrying much about main plot.