Visions and Biography.
Biography worked during the prologue. Afterwards it never recorded again until a couple of weeks ago. I'm about to start Act 3, I believe (going to the animancy hearings after talking to Lady Webb), so now I have a lot of biography info missing between the prologue and sometime of gameplay before the current point of the game I'm in. Also, only two recent visions regarding the latest quests I've completed, nothing else before that.
Maybe this is a hard thing to fix without having to restart the game, but I would really like to "unlock" all the missing entries in my current playthrough because I feel it breaks the immersion to have these "holes" in the journal.
In a game where the story and the character development are so important (and arguably the main qualities) such an issue should really not exist.
Other than that, there's the Psychic Backlash bug, which I think is already being looked at.
Oh, and some audio issues, like background audio playing when it's not supposed to. For me, just outside the Stronghold's main hall, there's the audio of the mobs (from a quest early in Act 2) still playing, even with no mob there anymore. Can't remember if I've seen anyone else complaining about this, but it's really annoying (also kinda breaks the immersion everytime I visit the stronghold ).