I have the same problem. My game crashes when I reach the Gilded Vale. It happened the first time when I tried to enter the Vale and then it worked for quite a while. Now I try to re-enter the Vale from the Eothas temple and it always crashes.
Is there any chance Obsidian fix this problem?
And by the way, why can't I upload my error-log file? Now I have to copy and paste it into this thread. I'd be thankful if someone could help me, all the stuff about corrupted fonts didn't work for me either.