Learn how to program in Squeak so you can add an obscure, relatively useless language to your resume.
I would reccommend trying to muscle your mind around Lisp and/or Scheme. You'll be a better programmer if you can figure them out since they use an entirely different style than programming in C, C++, Java, ObjC, C#, etc.
A lot of buisness are moving to web development models and rich internet applications. Knowing how to use a hypertext preprocessor language like PHP, JSP, ColdFusion, ASP, ASP.Net as well as JavaScript, X/HTML, XML, and Javascript can help you in the buisiness world. Macromedia's Flex system is another area of RIAs but it's really expensive while most of the others are pretty cheap to free.
Most games are done in C/C++ and Assembly although Sun has recently started an initiative to make Java a viable game-programming language.
